Detection of quinoline drugs

Quinoxalines are a class of chemically synthesized animal specific drugs with the basic structure of quinoxoline-N1, N4 dioxide. They have broad-spectrum antibacterial, feed conversion improvement, and growth promoting effects. Currently, quinoxaline drugs mainly include cyadox (CYX), carbadox (CBX), olaquindox (OLQ), methylquine (MQX), quinolone (QCT) Cinoquidox (CQD) and drazidox (DZX), among others. The research and application of this type of drug can be roughly divided into three aspects: the first is its therapeutic effect on animal diseases, the second is its growth promoting effect on animal production, and the third is the study of residue and toxicity. Quinoxaline drugs are mostly insoluble in water and soluble in organic solvents such as dimethyl sulfoxide and dimethylformamide. They often form yellow or light yellow crystals and are unstable when exposed to light. The properties of commonly used quinoline drugs are shown in Table 15-1

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